Pep Guardiola said he was warned by club doctors that top scorer Sergio Aguero could be ruled out until January if he aggravated a muscle injury.
The Argentina international missed Saturday’s 3-1 win over Bournemouth and is doubtful to face Watford and Chelsea this week.
“The doctors told me (on Friday) Sergio cannot play,” Guardiola said. “If he plays, maybe it’s four or five weeks off. In that situation, this month, with a lot of games, he was not safe.
City’s all-time top scorer appears unlikely to make the trip to Vicarage Road on Tuesday or Stamford Bridge on Saturday.
“Right now, I’m not quite sure,” Guardiola said when asked about the availability of Aguero, who has eight Premier League goals this season.
“I speak with the doctors every day, they make a report and a briefing,” he added. “They say ‘ready’ or ‘not ready’ and we decide.”
Aguero’s form has limited the Brazilian’s playing time recently but the 21-year-old said he was ready to contribute if needed following his own injury concerns, which saw him miss last week’s Champions League win over Lyon.